منابع مشابه
Shear stress and flow-mediated dilation.
In this edition of Hypertension, the Framingham Heart Study group reports on the relationship between diastolic shear stress and brachial artery flow mediated dilation (FMD) in 2045 participants of the Framingham Offspring group.1 Clinical correlates and heritability of FMD in the participants have been published previously.2 The new report1 challenges conventional concepts on endothelial funct...
متن کاملLocal Shear Stress and Brachial Artery Flow–Mediated Dilation
Endothelium-dependent flow-mediated dilation is a homeostatic response to short-term increases in local shear stress. Flow-mediated dilation of the brachial artery in response to postischemic reactive hyperemia is impaired in patients with cardiovascular disease risk factors and may reflect local endothelial dysfunction in the brachial artery. However, previous studies have largely neglected th...
متن کاملFlow-Mediated Dilation: Just a Marker of Local Shear Stress?
Local Shear Stress? To the Editor: We read with interest the article by Mitchell et al1 and agree that flow-mediated dilation (FMD%) response may be partially explained by shear stress (diastolic shear stress [DSS]) or flow changes.2 However, this does not necessarily mean that risk factors do not influence the vascular response. Indeed, Megnien et al3 showed that shear stress reduction provoke...
متن کاملFlow-mediated dilation: just a marker of local shear stress?
Local Shear Stress? To the Editor: We read with interest the article by Mitchell et al1 and agree that flow-mediated dilation (FMD%) response may be partially explained by shear stress (diastolic shear stress [DSS]) or flow changes.2 However, this does not necessarily mean that risk factors do not influence the vascular response. Indeed, Megnien et al3 showed that shear stress reduction provoke...
متن کاملShear stress and flow-mediated dilation: all shear responses are not created equally.
SINCE THE INTRODUCTION OF brachial artery reactivity testing in 1992 by Celermajer et al. (1), the measurement of endothelial function with the use of high-frequency ultrasonography of the brachial artery has proven to be an effective research tool for the assessment of cardiovascular risk (16). To date, 12 publications have demonstrated that endothelial dysfunction as measured by impaired flow...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2004
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000137301.99716.e8